Remicade Approved for Ulcerative Colitis

  • Friday, 22 July 2011
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If you are like me and you think what this indicates then you have an idea of my concerns.  If you aren't like me here are a few of my concerns -
 
First of all I have to ask just why is a *kid* getting UC.  Then I ask, why do you need to select a drug that is genetically engineered and one that costs up to $25,000 a year and is administered by IV (intravenous).
 
Next think about the risks of the drug -
 
Risks include: SOURCE

  • serious and sometimes fatal blood disorders
  • serious infections
  • lymphoma and solid tissue cancers
  • reports of serious liver injury
  • reactivation of hepatitis B
  • reactivation of tuberculosis
  • lethal hepatosplenic T-cell lymphoma (Generally only when combined with 6-mercaptopurine)
  • drug-induced lupus
  • demyelinating central nervous system disorders
Cases of leukopenia , neutropenia , thrombocytopenia , and pancytopenia (some fatal) have been reported with infliximab. [18] The FDA issued a warning to doctors appearing in the respective product labeling of infliximab instructing them to screen and monitor potential patients more carefully. [19] The FDA issued a warning to doctors that there is an increased risk of lymphoma and other cancers associated with the use of infliximab and other tumor necrosis factor (TNF) blockers in children and adolescents...

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